Estropausal gut microbiota transplant improves measures of ovarian function in adult mice.

Nat Aging · 2026 · PMC13004687 · PMID 41776310

Europe PMC DOI

hedged sentences

0.1726

closest p · 3.5× alpha

0.3759

boldest claim

The sentences

a suggestive trendP value ~ 0.1726not close (p > 0.1)

There was a suggestive trend for increased litter size in FMT-EF mice ( P value ~ 0.1726; Fig. 4c ).

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a nonsignificant trendP value ~ 0.3759not close (p > 0.1)

To further assess whether estrobolome-associated pathways might be affected with age, we examined changes in β-glucuronidase activity in female mice predicted using PICRUSt2, which revealed a nonsignificant trend of decreased β-glucuronidase activity with age ( P value ~ 0.3759; Fig. 1i ).

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