Oxytocin attenuates isolation-evoked emotional and social behavioral dysregulation through neural, immune, and microbiota mechanisms.

Transl Psychiatry · 2026 · PMC13004923 · PMID 41667420

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.1500

boldest claim

The sentences

showed a trendP = 0.09so close (0.05 < p ≤ 0.1)

When mice reached the end of the open arm in the EPM, the GCaMP7s signal in the NaCl-C57-SI group showed a trend toward a higher AUC compared to the OXT-C57-SI group ( P = 0.09, Fig. 6C ).

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a decreasing trendP = 0.15not close (p > 0.1)

However, serum OXT levels were notably lower in the C57-SI group ( P < 0.05), and a decreasing trend was observed in PFC OXT levels ( P = 0.15, Fig. 3B ).

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