Pregnanolone-Based Prodrugs as a Strategy for Neuroprotective Drug-Like Compounds: Pregnanolone Pyroglutamate and Its Age‑dependent Anticonvulsant Effects in the 6-hz Seizure Model in Immature Rats.

Drug Des Devel Ther · 2026 · PMC13005588 · PMID 41868175

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did not reach statistical significanceno p-value reported

The effect of the 5 mg/kg dose did not reach statistical significance.

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