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Dupilumab Dampens Mucosal Type 2 Response During Acetylsalicylic Acid Challenge in N-ERD Patients.

Clin Exp Allergy · 2026 · PMC13006153 · PMID 41309110

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While nasal baseline leukotriene levels showed a trend towards reduction after dupilumab treatment (Table S3 ), as previously shown [ 15 ], we were surprised that N‐ERD patients still expressed substantial amounts of LTE 4 after the second ASA provocation (Figure 4A and Figure S5A ).

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