only marginally significantP = 0.080
However, after adjusting for UACR reduction, the direct effect remained only marginally significant (β = 5.88; 95% CI: –0.50 to 10.74; P = 0.080), and the path from UACR reduction to eGFR change was not significant (β = 0.00; 95% CI: –0.04 to 0.04; P = 0.871).