Safety and Efficacy of Mesotherapy with Placenta Polypeptide Injection for Moderate-to-Severe Sensitive Skin: A Multicenter, Randomized, Controlled Trial.

Clin Cosmet Investig Dermatol · 2026 · PMC13006345 · PMID 41878549

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highly significantno p-value reported

16 , 30 The highly significant improvement observed in the GAIS scores further corroborates the clinical benefit of PPI.

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did not reach statistical significanceno p-value reported

While these transient changes did not reach statistical significance individually, they may represent part of a continuum of skin repair and anti-inflammatory effects that collectively manifest as the significant improvement captured by the primary endpoint at the final visit.

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