Maternal 12-HETE is associated with childhood asthma and the responses to prenatal omega-3 supplementation.

45 Similar to the results from the FFQ estimated dietary n-3 LCPUFA intake, we found that among mothers with detectable 12-HETE levels, high maternal CMPF levels, i.e., above the median, showed a trend toward a reduced risk of childhood asthma from birth to 6 years: aHR = 0.79; 0.60–1.03; p = 0.082, whereas there was no association among mothers with undetectable levels: aHR = 0.94; 0.55–1.60; p = 0.820 ( Figure 5 B).

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