An exhaustive cell-based screen coupled with an intracellular-induced lux-based reporter identified bioactive molecules that inhibit host cell infection by intracellular pathogens.

Notably, although the inhibition of compound C7 on Salmonella replication did not reach statistical significance, the mean intracellular replication value was low by more than 30% relative to the Salmonella replication in the absence of the compounds (Ctrl; Figure 3B ).

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