Schlafen 11 as a prognostic and potentially predictive biomarker in soft tissue sarcoma: evidence from a real-world cohort.

Front Oncol · 2026 · PMC13008703 · PMID 41883956

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

showed a trendp = 0.054so close (0.05 < p ≤ 0.1)

In univariate analyses, high SLFN11 expression showed a trend toward longer OS (HR 0.35, p = 0.054) and a significant association with longer PFS (HR 0.35, p = 0.038) ( Supplementary Table 11 ).

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a statistical trendno p-value reported

For survival analyses, Kaplan-Meier curves, a log-rank test, univariate analyses, and a multivariable Cox proportional hazards model were used, with a p-value ≤ 0.05 considered significant and a p-value ≤ 0.1 considered a statistical trend.

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