Barely Significant
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An IL6 variant -174 G-C alters cardiac hypertrophy but not cardiometabolic responses to HFD in mice.

NPJ Metab Health Dis · 2026 · PMC13009176 · PMID 41872508

1
hedged sentence
0.0521
closest p · 1.0× alpha
0.0521
boldest claim

The sentences

did not reach statistical significancep = 0.0521so close (0.05 < p ≤ 0.1)
Increased cardiac Il6 mRNA expression was observed in female CC variant mice, a trend that was also observed in male CC variant mice but did not reach statistical significance ( p = 0.0521, Fig. 5E ).

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