Molecular profile and targeted therapies for ovarian clear cell ovarian cancer.

According to Bolton et al., there was a trend toward a higher frequency of ARID1A -mutated tumors in women of East Asian descent compared to other groups, though this difference did not reach statistical significance. 30 Their molecular clustering further revealed that the TP53 -mutant, ARID1A wild-type cluster was predominantly enriched for advanced-stage disease and associated with worse survival outcomes. 30 In contrast, tumors belonging to the ARID1A -mutant clusters were more likely to occur in ind

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