Clinical efficacy and safety of short-length peroral endoscopic myotomy (POEM) compared with long-length myotomy for the treatment of achalasia.

Ther Adv Gastrointest Endosc · 2026 · PMC13009758 · PMID 41883560

Europe PMC DOI

hedged sentences

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

did not reach statistical significancep = 0.068so close (0.05 < p ≤ 0.1)

19 , 21 , 37 , 38 LES pressure at follow-up manometry at 6–12 months was lower in the long myotomy group compared to the short myotomy group, (12.7 ± 7.6–27.8 vs 23.2 ± 14.9–28.4) but did not reach statistical significance ( p = 0.068).

also in 111,027 other papers

borderline significanceno p-value reported

They found that full-thickness myotomy was associated with a higher incidence of GERD (CI: 0.05 (−0.00, 0.10], p = 0.06), as was anterior myotomy (CI: −0.09 (−0.20, 0.01), p = 0.07, I 2 = 0%), both with borderline significance.

also in 7,017 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.