A Single-Cell Atlas of Pan-Cancer Liver Metastasis Reveals Dynamic Cellular Programs Driving Metastatic Progression and Immune Modulation.

Research (Wash D C) · 2026 · PMC13010057 · PMID 41884334

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Since NK_NKG7 showed a trend toward poorer overall survival (Fig. 5 D), it may contribute to immune tolerance within the liver metastatic TME by recruiting Tregs, potentially promoting immune evasion and leading to poorer cancer survival outcomes.

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