Responsive neurostimulation in children, adolescents, and young Adults-Longitudinal effectiveness and safety.

Neurotherapeutics · 2026 · PMC13010426 · PMID 41863185

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

near-significantp = 0.06so close (0.05 < p ≤ 0.1)

Concurrent surgery showed a near-significant benefit (HR = 1.98, 95 % CI: 0.96–4.06, p = 0.06).

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near significanceno p-value reported

With recurrent event analysis, we identified concurrent epilepsy surgery as a positive modifier of sustained effectiveness at the AR level and near significance at the SR level, pointing to the known efficacy of epilepsy surgery [ 9 ].

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