Barely Significant
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Clinical review: Menopause hormone therapy in weight management.

Obes Pillars · 2026 · PMC13010941 · PMID 41883510

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A 2019 meta-analysis of 12 RCTs involving 4474 postmenopausal women found a trend toward lean mass preservation with MHT use; however, the difference did not reach statistical significance [ 59 ].

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