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Optimal sequencing of brain radiotherapy and immunotherapy for patients with non-small cell lung cancer and driver gene-negative, asymptomatic brain metastases.

BMC Cancer · 2026 · PMC13011518 · PMID 41692709

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Concurrent administration of ICIs and brain RT resulted in prolonged OS compared with sequential treatment, although the difference did not reach statistical significance, and the concurrent approach did not increase the risk of adverse events (AEs).

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