Serum p-tau217 Is a Prognostic Indicator of Cognitive Impairment in Idiopathic REM Sleep Behavior Disorder.

Ann Neurol · 2026 · PMC13011788 · PMID 41312760

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hedged sentences

0.0600

closest p · 1.2× alpha

0.0700

boldest claim

The sentences

borderline significantp = 0.06so close (0.05 < p ≤ 0.1)

There was a weak positive correlation between storage time and NfL levels ( ρ = 0.14, p = 0.02) and a weak, borderline significant correlation with p‐tau217 levels ( ρ = 0.11, p = 0.06), as shown in Figure S2 .

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did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

Serum p‐tau217 levels were higher in the APOE ε4 carriers (n = 37; median ± IQR = 0.80 ± 0.69pg/mL) compared to the non‐carriers (n = 52; median ± IQR = 0.57 ± 0.56pg/mL), as shown in Figure S 10 , but the difference did not reach statistical significance ( p = 0.07).

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