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The efficacy of a novel CO<sub>2</sub> topical vapocoolant spray for reducing needle-related pain in dogs.

Front Vet Sci · 2026 · PMC13011815 · PMID 41884302

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Although both cryoanesthesia groups showed reduced pain levels during FNA and jugular venipuncture procedures, the differences did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.