Molecular role of developmentally regulated GTP-binding protein 1 in coordinating osteoclast and osteoblast differentiation during bone remodeling.

RANKL injection successfully induced bone loss in the calvaria; co-administration of Drg1 -siRNA with RANKL resulted in a greater degree of bone loss compared to RANKL alone, although the difference did not reach statistical significance ( Fig. 6 B).

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