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A systematic evaluation of grayscale conversion methods for mitigating color variation in deep learning-based histopathological image analysis.

J Pathol Inform · 2026 · PMC13015737 · PMID 41889534

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In contrast, although the ACSRM candidate demonstrated improved precision and AUC on the unfamiliar distribution, it did not reach statistical significance in terms of overall prediction discordance compared to the baseline.

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