Barely Significant
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Functional characterisation of obesity-associated MRAP2 variants on MC4R and GHSR signalling.

Hum Mol Genet · 2026 · PMC13017093 · PMID 41758604

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showed a trendP = 0.05actually significant
MRAP2 variants S80F and R125C showed a trend towards decreasing GHSR cell surface expression compared to control (77.1 ± 6.9% and 72.3 ± 11.7% respectively; P = 0.05 and 0.08 respectively; Fig. 8C ).

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