ChemR23 prevents phenotypic switching of vascular smooth muscle cells into macrophage-like foam cells in atherosclerosis.

While body weight, leucocyte counts, and lipid profiles remained unaffected (see Supplementary material online , Table S5 ), C9 treatment significantly reduced atherosclerotic lesion size in the aortic root, whereas α-NETA showed a trend towards reduction ( Figure 8 B ).

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