TREC dynamics as a biomarker of naive T-cell homeostasis in traumatic brain injury: a longitudinal analysis.

Front Med (Lausanne) · 2026 · PMC13018110 · PMID 41907251

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did not reach statistical significancep = 0.081so close (0.05 < p ≤ 0.1)

a positive trendno p-value reported

Days since hospitalization showed a positive trend but did not reach statistical significance at this stage ( p = 0.081) ( Supplementary Table S4 ).

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a decreasing trendno p-value reported

an increasing trendno p-value reported

For TREC, 18 patients exhibited an increasing trend over time, while 11 showed a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.