Malignancy in anti-synthetase syndrome: clinical features and prognostic impact from a multicenter retrospective study.

Front Med (Lausanne) · 2026 · PMC13018139 · PMID 41907254

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.1380

boldest claim

The sentences

a trend toward significanceP = 0.067so close (0.05 < p ≤ 0.1)

showed a trendP = 0.067so close (0.05 < p ≤ 0.1)

ASyS diagnosis showed a trend toward significance (OR 1.85, 95% CI 0.96–3.58, P = 0.067).

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did not reach statistical significanceP = 0.138not close (p > 0.1)

However, the difference in survival distribution between these two subgroups did not reach statistical significance in this cohort (log-rank P = 0.138), likely due to the limited sample size ( Figure 2 ). 4.

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borderline significanceno p-value reported

The small sample size of the ASyS-MAL subgroup limited the statistical power for several comparisons, including the survival analysis and likely contributed to the borderline significance of anti-Ro-52 in the adjusted model.

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