Enhancing the transduction efficiency of lentiviral vectors in CAR-T cell therapy through an optimization workflow.

Front Med (Lausanne) · 2026 · PMC13018915 · PMID 41907291

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a clear trendno p-value reported

In this context, our data demonstrate a clear trend toward improvement and lay the groundwork for future refinement using complementary strategies such as plasmid concentration and purity, coating plates, other transfection reagents, or even exploring newer compounds such as BX795 or Vectofusin-1 ( 44 – 46 ).

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