a nonsignificant trendP=0.06
The study demonstrated a nonsignificant trend toward reduced tubulointerstitial fibrosis (P=0.06) in the eplerenone group but failed to show significant changes in albuminuria, blood pressure, or estimated GFR (eGFR).
The study demonstrated a nonsignificant trend toward reduced tubulointerstitial fibrosis (P=0.06) in the eplerenone group but failed to show significant changes in albuminuria, blood pressure, or estimated GFR (eGFR).
Finerenone reduced the risk of heart failure hospitalization by 20% and all-cause mortality by 14%, though reductions in cardiovascular death and renal failure did not reach statistical significance.