However, there was a clear trend that the 2 μg dose also induced the highest IgG antibody titers in several cases and this result aligns with our previous results as we have previously demonstrated that high antigen dose dampens the neutralizing antibody levels [ 17 , 55 ].
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Coxsackie B1 virus-like particle that lacks VP4 protein demonstrates improved vaccine scalability, stability and immunogenicity.
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