One-month early time-restricted eating enhances cognition via white matter-cortical pathways in males with metabolic syndrome: evidence from TBSS and SBM analyses.

Front Nutr · 2026 · PMC13021466 · PMID 41909043

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did not reach statistical significanceno p-value reported

TG, HDL-C, LDL-C, and hs-CRP showed a tendency toward improvement, but the changes did not reach statistical significance.

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marginal significanceno p-value reported

The marginal significance of individual paths may reflect the modest sample size ( n = 21), but the robust bootstrap test of the indirect effect provides confidence in the mediation pattern ( Figure 3 ).

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