Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colorectal cancer (HIPECT4): final analysis of randomized clinical trial.

BJS Open · 2025 · PMC13023033 · PMID 41891861

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did not reach statistical significanceno p-value reported

However, OS and DFS at 36 months did not reach statistical significance between groups.

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