did not reach statistical significancep = 0.0936
qPCR analysis showed that at the mRNA level, the expression in the BIDC group was significantly lower than in the NBIS group ( p = 0.0130), about 0.2 times that of the NBIS group; although the BILC group was higher than the NBIS group, the difference did not reach statistical significance ( p = 0.0936, approximately 1.6 times that of the NBIS group).