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Effects of Melatonin and <i>Akkermansia muciniphila</i> on the Gut-Liver Axis in a MASLD-Associated Liver Fibrosis Model: An Integrative Multi-Omic Approach.

Antioxidants (Basel) · 2026 · PMC13023461 · PMID 41897453

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showed a trendno p-value reported
At the molecular level, melatonin treatment significantly decreased hepatic expression of Tlr4 , Tgfb1 and Timp1 , and showed a trend towards reduced expression of Tnf , Tlr2 , Nlrp3 and Acta2 ( Figure 2 D).

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