Novel Insights on Benzo[<i>b</i>]thiophene Analogues for MAO-B Inhibition and Neuroprotection: Design, Synthesis, Molecular Modelling Studies and Biological Activity.

Interestingly, although all compounds showed comparable effects after 48 h, at the longer observation time (i.e., 72 h) compounds 11 and 12 displayed a slight protective trend, comparable to that of the clinically used drug ( R )-(−)-Deprenyl (100 μM), although this did not reach statistical significance ( Figure 7 and Figure S1 ). 3.3.

also in 111,027 other papers