Predictors of Response to Occipital Nerve Stimulation in Patients with Refractory Chronic Cluster Headache: Protocol for a Prospective Observational Study.

To facilitate interpretation and transparent reporting of the results, the following graphical outputs are pre-specified as part of the analytical plan: (a) Receiver Operating Characteristic (ROC) curves displaying sensitivity versus 1-specificity for each individual biomarker showing significant or near-significant bivariate associations with treatment response, as well as for the combined multivariable models (Elastic Net and Random Forest), enabling visual comparison of univariate versus multivariate discriminative performance; (b) a dot plot or bar chart of variable importance scores derived from the Elast

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