Barely Significant
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Micro- and Macro-Vascular Disease in Systemic Sclerosis and Very Early SSc (VEDOSS): Results from a Monocentric Observational Study.

Biomedicines · 2026 · PMC13024536 · PMID 41898254

1
hedged sentence
0.1200
closest p · 2.4× alpha
0.1200
boldest claim

The sentences

did not reach statistical significancep = 0.12not close (p > 0.1)
Specifically, the presence of plaques, stenosis, or occlusions in the carotid, aortic, or lower limb arterial districts, as well as aneurysmal dilations > 3 cm, was more frequent in SSc (52.9%) and VEDOSS (50%) compared with PRP controls (21.4%), although the difference did not reach statistical significance ( p = 0.12).

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