Dimercaprol Reprograms Intestinal Redox Homeostasis and Organelle Crosstalk to Combat Iron-Induced Gut Dysbiosis Through NRF2/HO-1 Signaling.

Antioxidants (Basel) · 2026 · PMC13024590 · PMID 41897502

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an increasing trendno p-value reported

did not reach statistical significanceno p-value reported

DP treatment significantly restored the expression of claudin-1 and ZO-1 in FC-treated IPEC-J2 cells, whereas occludin showed an increasing trend that did not reach statistical significance ( Figure 4 A).

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a decreasing trendno p-value reported

Moreover, DP significantly reduced FC-induced IL-6 protein levels, while IL-1β and TNF-α showed a decreasing trend that did not reach statistical significance ( Figure 4 E).

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