Association Between HLA Polymorphisms and Non-Alcoholic Fatty Liver Disease in Patients with Rheumatoid Arthritis: An Observational Study.

Diseases · 2026 · PMC13024850 · PMID 41892014

Europe PMC DOI

hedged sentences

0.1210

closest p · 2.4× alpha

0.1210

boldest claim

The sentences

showed a trendp = 0.121not close (p > 0.1)

HLA-B*07 also showed a trend-level association (OR = 2.33, 95% CI [0.79, 6.50], p = 0.121, p adj = 0.642).

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highly significantno p-value reported

In a study of 138 NAFLD patients and controls, HLA-DRB1*15 and HLA-DRB1*16 differed markedly between individuals with steatosis and metabolic syndrome and the control group; notably, the difference for HLA-DRB1*16 remained highly significant even in the absence of metabolic syndrome [ 29 ].

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