Characterization of HER2-Positive Murine Breast Cancer Models for Investigating HER2-Targeted Therapy and Immunotherapy.

Cancers (Basel) · 2026 · PMC13024896 · PMID 41899598

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

nearly significantno p-value reported

HER2 YVMA overexpression in 4T1 models led to a nearly significant increase in the frequency of spontaneous brain metastasis, with 1/5 HER2-negative mice developing metastasis compared to 8/10 across the HER2-expressing groups (Fisher’s Exact Test p = 0.0889).

also in 3,287 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.