Effects of Citicoline-Based Supplementation on Lipid Peroxidation Markers and Sirtuin-1 Expression in Ischemic Stroke.

Curr Issues Mol Biol · 2026 · PMC13024967 · PMID 41899465

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did not reach statistical significanceno p-value reported

At baseline, ischemic stroke patients showed a tendency toward higher SIRT1 expression compared with healthy controls, although this difference did not reach statistical significance.

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a decreasing trendno p-value reported

Following supplementation, 8-iso-PGF 2 α levels increased in patients with comorbidities, particularly diabetes mellitus (DM), whereas an exploratory analysis suggested a decreasing trend in patients without comorbidities.

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