In H9c2 cells, pharmacological inhibition of MPTP with cyclosporin A (CsA) confirmed assay sensitivity by significantly delaying pore opening relative to VC, whereas MiD knockdown and Mfn2 overexpression showed only a trend toward delayed opening that did not reach statistical significance ( Supplementary Figure S4B ).
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Mitochondrial Dynamic Proteins MiD49 and MiD51 as Novel Targets of Cardioprotection.
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