Mutant KRAS Heterogeneity Shapes Nuclear Architecture During Pancreatic Cancer Initiation.

Epigenomes · 2026 · PMC13025234 · PMID 41892368

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did not reach statistical significanceno p-value reported

Although these changes did not reach statistical significance, the trend toward volumetric compaction parallels the reduction in nuclear area detected by 2D analysis, supporting consistent nuclear condensation following G12D induction.

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