Is Pulse Co-Oximetry a Reliable Alternative to Invasive Hemoglobin Measurement in Pediatric Neurosurgical Procedures?

Children (Basel) · 2026 · PMC13025390 · PMID 41897036

Europe PMC DOI

hedged sentence

0.0750

closest p · 1.5× alpha

0.0750

boldest claim

The sentences

did not reach statistical significancep = 0.075so close (0.05 < p ≤ 0.1)

In the overall cohort (n = 208), higher fluid intensity (defined as >19.0 mL/kg, the cohort median) did not degrade performance; instead, SpHb demonstrated a stronger correlation (r = 0.631) compared to the lower intensity group (r = 0.456), though this difference did not reach statistical significance ( p = 0.075).

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