Inflammation-Driven Downregulation of CYP2E1 Is Associated with Attenuated Diethylnitrosamine (DEN)-Induced Hepatocarcinogenesis.

Cells · 2026 · PMC13025445 · PMID 41892336

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did not reach statistical significanceno p-value reported

Mice pretreated with CCl 4 (CCl 4 + DEN) showed reduced tumor multiplicity per mouse, whereas total tumor burden per mouse tended to be lower but did not reach statistical significance ( Figure 6 E).

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