Interplay Between p53 and Wnt/β-Catenin Signaling in Colorectal Cancer: Associations with Mismatch Repair Status, Tumor Microenvironment, and Clinicopathological Outcomes.

Curr Oncol · 2026 · PMC13025743 · PMID 41892206

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After adjustment, aberrant p53 showed a trend toward increased mortality (HR: CSS 3.56; OS 2.52), and low Wnt3 tended to be associated with poorer CSS (HR 2.59), whereas neither β-CTN index was prognostic.

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