Dynamic immune reconstitution and clinical outcomes in different chimerism statuses of HLA-matched transplantation for severe aplastic anemia.

Stem Cells Transl Med · 2026 · PMC13026414 · PMID 41894587

Europe PMC DOI

hedged sentences

0.0830

closest p · 1.7× alpha

0.0830

boldest claim

The sentences

did not reach statistical significanceP = .083so close (0.05 < p ≤ 0.1)

Notably, in the MC group, patients who developed GF had poorer 5-year OS, although this difference did not reach statistical significance (75.0% [95% CI, 54.1-100] vs 100%, P = .083; Figure 2C ).

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a nonsignificant trendno p-value reported

6 , 7 Notably, patients with MC who experienced GF had a nonsignificant trend toward poorer 5-year OS than their GF-free MC counterparts did (75.0% vs 100%), a finding likely limited by the small number of events.

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