Nevertheless, while our results establish a clear trend between MX2 upregulation and enhanced apoptosis, the causal role of MX2 in regulating UV-induced cell death remains to be functionally validated.
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Genotype-Encoded UV Sensitivity in iPSC-Derived Human Melanocytes Reveals MX2 as a Physiological Amplifier of p53/p38-Mediated DNA Damage Signaling.
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