Exploratory transcriptomic analysis of mouse articular cartilage in response to tissue inhibitor of metalloproteinase 3 identifies inflammation-associated gene expression changes.

Front Immunol · 2026 · PMC13027204 · PMID 41909687

Europe PMC DOI

hedged sentence

0.0510

closest p · 1.0× alpha

0.0510

boldest claim

The sentences

did not reach statistical significanceP = 0.051so close (0.05 < p ≤ 0.1)

This supports the trend observed by RNA-seq, which showed a log 2 FC of 0.6 that did not reach statistical significance (P = 0.051; Figure 4D ).

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