Inflammatory Load Across Diabetes Duration: CRP and ESR Patterns and Their Metabolic Correlates.

Metabolites · 2026 · PMC13028298 · PMID 41893351

Europe PMC DOI

hedged sentences

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

did not reach statistical significancep = 0.063so close (0.05 < p ≤ 0.1)

Although this pattern suggested a U-shaped distribution, the overall difference across groups did not reach statistical significance (Kruskal–Wallis p = 0.063).

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borderline significantno p-value reported

CRP and ESR demonstrated moderate positive correlations with functional CKD (ρ = 0.350 and ρ = 0.429, respectively; p < 0.001), whereas their association with ASCVD was weaker and, in the case of CRP, borderline significant.

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