Gastrointestinal Toxicity and Clinical Predictors of Total Neoadjuvant Therapy in Rectal Cancer: A Real-World Retrospective Study.

Life (Basel) · 2026 · PMC13028580 · PMID 41900941

Europe PMC DOI

hedged sentences

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closest p

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boldest claim

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did not reach statistical significanceno p-value reported

9.1%; p = 0.242) did not reach statistical significance.

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borderline significanceno p-value reported

TNT treatment and female sex remained associated with an increased risk of GI AEs, with p values within the range of statistical significance or borderline significance, while age did not demonstrate an independent effect.

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