a strong trendp = 0.056
Neurodegeneration Two-way ANOVA for cortical proBDNF (37 kDa) revealed a strong trend toward an overall ‘genotype’ effect [F(1,40) = 3.860, p = 0.056], where proBDNF was elevated in APP/PS1 mice, and a significant ‘genotype’ by ‘treatment’ interaction [F(1,40) = 5.580, p = 0.02].