An Injectable Thermosensitive Chitosan/Astaxanthin/Ibuprofen Hydrogel Mitigates High-Voltage, Low-Current Electrical Burn Injury Through Inhibition of ROS-NF-κB Signaling-Mediated Inflammation.

Pharmaceutics · 2026 · PMC13029109 · PMID 41900809

Europe PMC DOI

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closest p · 0.2× alpha

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boldest claim

The sentences

nominally significantp -value < 0.01actually significant

Enriched GO terms and KEGG pathways were considered nominally significant at a p -value < 0.01 according to Fisher’s exact test. 2.17.

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an increasing trendno p-value reported

The Z score—calculated as the difference between the number of upregulated and downregulated genes associated with a given GO term divided by the square root of the total number of genes annotated to that term—revealed an increasing trend for the ROS signaling pathway.

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